BDBM380821 8-(2,3-Dihydro-benzo[1,4]dioxin-6- yl)-3,4-dihydro-1H- pyrano[4,3-c]pyridin-4-ol, Enantiomer I::US9890171, 25::US9890171, 38

SMILES OC1COCc2c1cncc2-c1ccc2OCCOc2c1

InChI Key InChIKey=VJTMAWHOKFDMIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380821   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380821(8-(2,3-Dihydro-benzo[1,4]dioxin-6- yl)-3,4-dihydro...)
Affinity DataIC50:  12nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380821(8-(2,3-Dihydro-benzo[1,4]dioxin-6- yl)-3,4-dihydro...)
Affinity DataIC50:  159nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent