BDBM380973 6-(4-Hydroxy-4-methyl-3,4-dihydro- 1H-pyrano[4,3-c]pyridin-8-yl)-1- methyl-1H-indazole-3-carbonitrile, Enantiomer I::US9890171, 177::US9890171, 178
SMILES Cn1nc(C#N)c2ccc(cc12)-c1cncc2c1COCC2(C)O
InChI Key InChIKey=IZBRBDMDXUPWCO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 380973
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 15nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 42.8nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair