BDBM381094 US9890185, Example 38(q)
SMILES COc1c(CNC(C)=O)cc(cc1NC(=O)Nc1ccc(Oc2ccnc(NCc3ccccn3)c2)c2ccccc12)C(C)(C)C
InChI Key InChIKey=FZGSPFYSRVCSSA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 381094
Affinity DataIC50: 6nMAssay Description:Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determinin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Method 1: The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.62E+3nMAssay Description:Method 2: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to t...More data for this Ligand-Target Pair
Affinity DataIC50: 383nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair