BDBM381396 4-chloro-1-(1,1-dioxidotetrahydro- 2H-thiopyran-4-yl)-N-(4- isopropylphenyl)-1H-pyrazolo[3,4- b]pyridine-5-carboxamide::US10272074, Example 229
SMILES CC(C)c1ccc(NC(=O)c2cnc3n(ncc3c2Cl)C2CCS(=O)(=O)CC2)cc1
InChI Key InChIKey=NWMNLAJUHTTWTP-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381396
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair