BDBM381556 1-[2-(4-Acetyl-piperazin-1-yl)- ethyl]-4-chloro-3-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-chloro-phenyl)- amide::US10272074, Example 391

SMILES CC(=O)N1CCN(CCn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(Cl)cc2)CC1

InChI Key InChIKey=XUYJQLMTIMVJCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381556   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381556(1-[2-(4-Acetyl-piperazin-1-yl)- ethyl]-4-chloro-3-...)
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent