BDBM381556 1-[2-(4-Acetyl-piperazin-1-yl)- ethyl]-4-chloro-3-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-chloro-phenyl)- amide::US10272074, Example 391
SMILES CC(=O)N1CCN(CCn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(Cl)cc2)CC1
InChI Key InChIKey=XUYJQLMTIMVJCH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381556
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair