BDBM381975 2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid::US10273222, Example 33

SMILES Cn1cnc(c1-c1ccc(Cl)cc1Cl)-c1cc(ccn1)C(O)=O

InChI Key InChIKey=SNYZZKKVKCUZEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 381975   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM381975(2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4-...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM381975(2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4-...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM381975(2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4-...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM381975(2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4-...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent