BDBM382052 2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridine-4- carboxylic acid::US10273222, Example 112

SMILES OC(=O)c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1

InChI Key InChIKey=HJHPUQDFLVHFFZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 382052   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM382052(2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridi...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM382052(2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridi...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM382052(2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridi...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM382052(2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridi...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quantscel Research

US Patent
LigandPNGBDBM382052(2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridi...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent