BDBM38224 US8546380, 1043::US8633188, 1043

SMILES CC1(CCSC(N)=N1)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F

InChI Key InChIKey=VVZZZUNCWSTIOI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 38224   

TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38224(US8546380, 1043 | US8633188, 1043)
Affinity DataIC50:  27nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38224(US8546380, 1043 | US8633188, 1043)
Affinity DataIC50:  27nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair