BDBM383290 4-(3-(3,4-difluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- triazaacenaphthalen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyridin-2-amine::US10278975, Compound I-54 R::US11376260, Example I-54R
SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(F)c(F)c3)c3nnc(c1)n23
InChI Key InChIKey=PYDBGLJLPSFVOL-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 383290
Affinity DataIC50: 0.0300nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair