BDBM383367 N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-dimethyl- 5,6,7,8-tetrahydro-5,8- methanocinnolin-8-yl)methyl)-N- ethyl-1-methyl-5- (trifluoromethyl)-1H-pyrazole-3- carboxamide::US10280144, Compound 94

SMILES CCN(C[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C)C(=O)c1cc(n(C)n1)C(F)(F)F

InChI Key InChIKey=RNZRETCYTOIOGD-MQNRADLISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383367   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383367(N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-dimethyl- ...)
Affinity DataIC50:  5.5nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent