BDBM383383 4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihydro-7H-6- oxa-1,2,2a1- triazabenzo[cd]azulen-4-yl)- N-(tetrahydro-2H-pyran-4- yl)pyrimidin-2-amine::US10278975, Compound I-110 R::US11376260, Example I-110R

SMILES Clc1cnn(C[C@H]2CCOc3cc(cc4nnc2n34)-c2ccnc(NC3CCOCC3)n2)c1

InChI Key InChIKey=VGLZDXAKJOOLLY-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 383383   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383383(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383383(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent