BDBM383561 1-methyl-6-(1-propylpiperidine-3-carbonyl)-2-naphthonitrile::US10280149, Example 70

SMILES CCCN1CCCC(C1)C(=O)c1ccc2c(C)c(ccc2c1)C#N

InChI Key InChIKey=ISAYTCQDSBMWDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383561   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383561(1-methyl-6-(1-propylpiperidine-3-carbonyl)-2-napht...)
Affinity DataIC50:  91.8nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent