BDBM383693 2-(6-(1-cyclobutyl-4-methylpiperidine-3-carbonyl)-2-methoxynaphthalen-1-yl)acetonitrile::US10280149, Example 182b

SMILES COc1ccc2cc(ccc2c1CC#N)C(=O)[C@@H]1CN(CC[C@@H]1C)C1CCC1

InChI Key InChIKey=BJDGGDWQTYWFQS-KSFYIVLOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383693   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383693(2-(6-(1-cyclobutyl-4-methylpiperidine-3-carbonyl)-...)
Affinity DataIC50:  1.12nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In DepthDetails US Patent