BDBM384202 3-(2,3-Dichlorophenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-b]pyrazine::US10280171, Example 122
SMILES Cc1c(N)nccc1C(=N)c1ncc(nc1N)N1CCC2(CCC[C@H]2N)CC1
InChI Key InChIKey=YKPSFYUUWIGQNJ-CQSZACIVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384202
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: 205nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair