BDBM384362 US9932327, Compound 33

SMILES CN1CCC(C(O)C1)c1c(O)cc(O)c2c1oc(\C=C\c1c(Cl)cccc1Cl)cc2=O

InChI Key InChIKey=NFTJDXGFOUFNKG-AATRIKPKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384362   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The Council Of Scientific & Industrial Research

US Patent
LigandPNGBDBM384362(US9932327, Compound 33)
Affinity DataIC50:  2nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The Council Of Scientific & Industrial Research

US Patent
LigandPNGBDBM384362(US9932327, Compound 33)
Affinity DataIC50:  16nMAssay Description:CDK-2/cyclin A (5-20 mU diluted in 50 mM Hepes pH 7.5, 1 mM DTT, 0.02% Brij35, 100 mM NaCl) was assayed against Histone H1 in a final volume of 25.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent