BDBM384376 US9932327, Compound 35

SMILES CN1CCC(C(O)C1)c1c(O)cc(O)c2c1oc(\C=C\c1cccc(F)c1)cc2=O

InChI Key InChIKey=PZXBPUJVINVNLU-AATRIKPKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384376   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The Council Of Scientific & Industrial Research

US Patent
LigandPNGBDBM384376(US9932327, Compound 35)
Affinity DataIC50:  30nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
The Council Of Scientific & Industrial Research

US Patent
LigandPNGBDBM384376(US9932327, Compound 35)
Affinity DataIC50:  466nMAssay Description:CDK-2/cyclin A (5-20 mU diluted in 50 mM Hepes pH 7.5, 1 mM DTT, 0.02% Brij35, 100 mM NaCl) was assayed against Histone H1 in a final volume of 25.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent