BDBM384545 2-(7-((5-cyclopropyl-3-(2,6- dichlorophenyl)isoxazol-4- yl)methoxy)-9-hydroxy-3- oxabicyclo[3.3.1]nonan-9-yl)- 4-fluorobenzo[d]thiazole-6- carboxylic acid::US9932332, 1
SMILES OC(=O)c1cc(F)c2nc(sc2c1)C1(O)C2COCC1CC(C2)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1
InChI Key InChIKey=RRNDTWMDXDACEP-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384545
Affinity DataIC50: 19nMAssay Description:The human FXRalpha LBD was expressed in E. coli strain BL21(DE3) as an N-terminally GST tagged fusion protein. The DNA encoding the FXR ligand bindin...More data for this Ligand-Target Pair