BDBM384545 2-(7-((5-cyclopropyl-3-(2,6- dichlorophenyl)isoxazol-4- yl)methoxy)-9-hydroxy-3- oxabicyclo[3.3.1]nonan-9-yl)- 4-fluorobenzo[d]thiazole-6- carboxylic acid::US9932332, 1

SMILES OC(=O)c1cc(F)c2nc(sc2c1)C1(O)C2COCC1CC(C2)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=RRNDTWMDXDACEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384545   

TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM384545(2-(7-((5-cyclopropyl-3-(2,6- dichlorophenyl)isoxaz...)
Affinity DataIC50:  19nMAssay Description:The human FXRalpha LBD was expressed in E. coli strain BL21(DE3) as an N-terminally GST tagged fusion protein. The DNA encoding the FXR ligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent