BDBM384593 4-({trans-4-[2- (fluoromethyl)morpholin- 4- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 3-27

SMILES FCC1CN(CCO1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N

InChI Key InChIKey=RIXGIPYNQVKNIB-BDWYFLKXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384593   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384593(4-({trans-4-[2- (fluoromethyl)morpholin- 4- yl]cyc...)
Affinity DataIC50:  8nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent