BDBM384617 4-{[trans-4-(3-oxa-8- azabicyclo[3.2.1]oct-8- yl)cyclohexyl]amino} quinazoline-6-carbonitrile::US9932350, 3-47

SMILES N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3C4CCC3COC4)c2c1

InChI Key InChIKey=JOPJVSXHLRASFS-MJYONLJCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384617   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384617(4-{[trans-4-(3-oxa-8- azabicyclo[3.2.1]oct-8- yl)c...)
Affinity DataIC50:  872nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent