BDBM384633 4-({trans-4-[4-(2-fluoro- 2- methylpropanoyl)piperazin- 1- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 6-5
SMILES CC(C)(F)C(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N
InChI Key InChIKey=XJCLPKSSHCDVJO-IYARVYRRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384633
Affinity DataIC50: 12nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair