BDBM384648 4-[(trans-4-{4- [cyclopropyl(hydroxy) acetyl]piperazin-1- yl}cyclohexyl)amino] quinazoline-6-carbonitrile::US9932350, 6-20

SMILES OC(C1CC1)C(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N

InChI Key InChIKey=WCLONIXUULMVLX-DDDLIOIYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384648   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384648(4-[(trans-4-{4- [cyclopropyl(hydroxy) acetyl]piper...)
Affinity DataIC50:  8nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent