BDBM385022 (S)-2-(3-((2-amino-4-methyl-6-((1-(methylthio)heptan-3-yl)amino)pyrimidin-5-yl)methyl)-4-methoxyphenyl)-2-methylpropanoic acid ::US10287253, Example 33

SMILES CCCC[C@@H](CCSC)Nc1nc(N)nc(C)c1Cc1cc(ccc1OC)C(C)(C)C(O)=O

InChI Key InChIKey=SOOBIBYBUXAXEH-IBGZPJMESA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385022   

TargetToll-like receptor 7(Homo sapiens (Human))
Apros Therapeutics

US Patent
LigandPNGBDBM385022((S)-2-(3-((2-amino-4-methyl-6-((1-(methylthio)hept...)
Affinity DataEC50: <100nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent