BDBM385388 (E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]pyrimidin-5-yl]oxymethyl]prop-2-en-1-amine::US10287270, Example 5::US10464928, Example 5::US10793552, Example 5

SMILES CO[C@H]1CCN(C1)c1ncc(OC\C(CN)=C\F)cn1

InChI Key InChIKey=JXYUYCVRGOBMGR-INJWIWPUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 385388   

TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385388((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...)
Affinity DataIC50:  32nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385388((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...)
Affinity DataIC50:  32nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385388((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...)
Affinity DataIC50:  32nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent