BDBM385545 US10287278, Example 7::US10647706, Example 7
SMILES CN=S(C)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O
InChI Key InChIKey=OZBFYAADCJRRIO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385545
Affinity DataIC50: >20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Affinity DataIC50: >200nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Affinity DataIC50: >200nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair