BDBM385949 US10287292, Compound 1.127::US11059825, Compound 1.127

SMILES O=C(N[C@H]1CCN(C1)c1nccn2cnnc12)c1ncn(n1)-c1ccccc1

InChI Key InChIKey=QPEDKZAZXMYGPX-ZDUSSCGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 385949   

TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM385949(US10287292, Compound 1.127 | US11059825, Compound ...)
Affinity DataIC50: <500nMAssay Description:Target compounds can be tested to determine their ability to bind with CXCR7 sites on MCF-7 and/or MDA-MB-435S CXCR7 transfected cells. Efficiency-ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM385949(US10287292, Compound 1.127 | US11059825, Compound ...)
Affinity DataIC50:  1.50E+3nMAssay Description:In order to more properly assess the binding efficacy of the compounds, radioligand binding assays were carried out in the presence of 100% human ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM385949(US10287292, Compound 1.127 | US11059825, Compound ...)
Affinity DataIC50: <500nMAssay Description:Target compounds can be tested to determine their ability to bind with CXCR7 sites on MCF-7 and/or MDA-MB-435S CXCR7 transfected cells. Efficiency-ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM385949(US10287292, Compound 1.127 | US11059825, Compound ...)
Affinity DataIC50: <500nMAssay Description:In order to more properly assess the binding efficacy of the compounds, radioligand binding assays were carried out in the presence of 100% human ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent