BDBM386137 N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)methyl)-1-((3- oxocyclobutyl)carbonyl)piperidin-3- yl)methanesulfonamide::US10287305, Example 91::US10508083, Example 91::US11292766, Example 91

SMILES CC(C)[C@@H]1CC[C@@H](CC1)OC[C@H]1[C@H](CCCN1C(=O)C1CC(=O)C1)NS(C)(=O)=O

InChI Key InChIKey=CNHUOAAIQKDLGA-LDTOTXGLSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386137   

TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386137(N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)met...)
Affinity DataEC50:  39nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386137(N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)met...)
Affinity DataEC50:  39nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386137(N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)met...)
Affinity DataEC50:  39nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent