BDBM386823 N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4-(2,3,6- trifluorophenyl)cyclohexyl)oxy)- methyl)piperidin-3- yl)methanesulfonamide::US10287305, Example 258::US10508083, Example 258::US11292766, Example 258

SMILES CS(=O)(=O)N[C@H]1CCCN([C@H]1CO[C@H]1CC[C@H](CC1)c1c(F)ccc(F)c1F)C(=O)C1CC1

InChI Key InChIKey=CSKNLLRCLSVFLI-ZXUOCUECSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386823   

TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386823(N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4-(2,...)
Affinity DataEC50:  0.720nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386823(N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4-(2,...)
Affinity DataEC50:  0.720nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386823(N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4-(2,...)
Affinity DataEC50:  0.720nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent