BDBM386864 N'-((2R,3S)-1- (cyclopropylcarbonyl)-2-(((cis-4- phenylcyclohexyl)oxy)methyl)- piperidin-3-yl)-N,N- dimethylsulfuric diamide::US10287305, Example 310::US10508083, Example 310::US11292766, Example 310

SMILES CN(C)S(=O)(=O)N[C@H]1CCCN([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)C1CC1

InChI Key InChIKey=PCRLCJKQYKUKAH-MALNDZBISA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386864   

TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386864(N'-((2R,3S)-1- (cyclopropylcarbonyl)-2-(((cis-4- p...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386864(N'-((2R,3S)-1- (cyclopropylcarbonyl)-2-(((cis-4- p...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386864(N'-((2R,3S)-1- (cyclopropylcarbonyl)-2-(((cis-4- p...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent