BDBM388015 1-(4-(isopropylamino)-5-(1-(2-morpholinoethyl)-1H-1,2,3-triazol-4-yl)pyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile, 2TFA::US10294229, Example 163

SMILES CC(C)Nc1cc(ncc1-c1cn(CCN2CCOCC2)nn1)-n1ccc2cc(cnc12)C#N

InChI Key InChIKey=RZPGFZIWFQTDBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388015   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM388015(1-(4-(isopropylamino)-5-(1-(2-morpholinoethyl)-1H-...)
Affinity DataIC50:  2nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent