BDBM388331 US10294246, Compound No. 28

SMILES OB(O)[C@H](Cc1coc2ccccc12)NC(=O)Cc1ccccc1OC(F)(F)F

InChI Key InChIKey=QBBIPVDMAQYALU-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388331   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM388331(US10294246, Compound No. 28)
Affinity DataIC50:  2.75E+3nMAssay Description:Measurement of Beta5 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human constitutive proteasome (1.25 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM388331(US10294246, Compound No. 28)
Affinity DataIC50: <50nMAssay Description:Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immunoproteasome (0.25 nM) and se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent