BDBM388640 US9944643, 4

SMILES COC(=O)Nc1ccc-2c(NC(=O)[C@@H](C)CCC[C@H](NC(=O)c3ccc(C[NH3+])c(c3)C3CC3)c3cc-2ccn3)c1

InChI Key InChIKey=NSIBYUWQSPFQSN-QYBDOPJKSA-O

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388640   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM388640(US9944643, 4)
Affinity DataKi:  30nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; J T B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent