BDBM388847 2-Chloro-N-(1-pyridin-2-ylethyl)-4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]benzamide::US10738052, Example 177::US11261191, Example 177::US9944645, 177

SMILES CC(NC(=O)c1ccc(cc1Cl)-c1cnc2ncc(n2c1)C1(CC1)c1ccc2ncccc2c1)c1ccccn1

InChI Key InChIKey=KCYOWGDZYYPPAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 388847   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388847(2-Chloro-N-(1-pyridin-2-ylethyl)-4-[3-(1-quinolin-...)
Affinity DataIC50: <500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388847(2-Chloro-N-(1-pyridin-2-ylethyl)-4-[3-(1-quinolin-...)
Affinity DataIC50: <500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388847(2-Chloro-N-(1-pyridin-2-ylethyl)-4-[3-(1-quinolin-...)
Affinity DataIC50: <500nMAssay Description:Briefly, histidine-tagged c-Met catalytic domain fusion protein was used for the assay. IC50 measurements were based on the degree of phosphorylation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent