BDBM388983 4-(8-[2-fluoro-4-(morpholin-4- ylmethyl)phenyl]-5-{[(3R)-1- methylpiperidin-3- yl]methoxy}imidazo[1,2- c]pyrimidin-7-yl)benzonitrile::US10800779, Example 95::US11401272, Example 95::US9944647, Example 95
SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc(CN4CCOCC4)cc3F)c3nccn23)C1
InChI Key InChIKey=RJBMGSXQAYNJCH-XMMPIXPASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 388983
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair