BDBM389574 N'-{2-[(E)-2-(4- fluorophenyl)vinyl]quinazolin-4-yl}- N,N-dimethylethane-1,2-diamine::US9951029, 68
SMILES CN(C)CCNc1nc(\C=C\c2ccc(F)cc2)nc2ccccc12
InChI Key InChIKey=VQCDKFOAXKSCRP-FMIVXFBMSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 389574
Affinity DataIC50: 811nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 7.02E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair