BDBM389625 (E)-1-(1-(2-cyano-3-cyclopropylacryloyl)azetidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide::US11345695, Example 53::US11840513, Example 53::US9951056, Example 53
SMILES NC(=O)c1cn(nc1-c1ccc(Oc2ccccc2)cc1)C1CN(C1)C(=O)C(=C\C1CC1)\C#N
InChI Key InChIKey=PJLKWGLQZCCOFS-XDHOZWIPSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 389625
Affinity DataIC50: >1.00E+3nMAssay Description:1× and 2× assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:The activity of the Examples and Analogs described herein, as inhibitors of BTK are demonstrated and confirmed by pharmacological in vitro assays. Ac...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:1x and 2x assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:1× and 2× assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair