BDBM390018 4-amino-1-[(3R)-1-[(E)-4- [cyclobutyl(methyl)amino]but-2- enoyl]-3-piperidyl]-3-(4- phenoxyphenyl)-6H-pyrrolo[2,3- d]pyridazin-7-one::US10323037, Example 31::US9951077, 31
SMILES CN(C\C=C\C(=O)N1CCC[C@H](C1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12)C1CCC1
InChI Key InChIKey=MGAMTNYNSUFVLX-XCBPRYKJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 390018
Affinity DataIC50: <10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair