BDBM390063 US10323037, Example 76::US9951077, 76

SMILES Nc1n[nH]c(=O)c2n(cc(-c3ccc(Oc4ccccc4)cc3F)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=ZQMBJORCMASICC-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390063   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390063(US10323037, Example 76 | US9951077, 76)
Affinity DataIC50:  505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390063(US10323037, Example 76 | US9951077, 76)
Affinity DataIC50:  505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent