BDBM390702 (S)-N6-(4-(Trifluoromethyl)phenyl)-1,2,3,4-tetrahydronaphthalene-2,6-diamine::US9957261, Example 44

SMILES N[C@H]1CCc2cc(Nc3ccc(cc3)C(F)(F)F)ccc2C1

InChI Key InChIKey=VUOAFDXLEKXYID-AWEZNQCLSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390702   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM390702((S)-N6-(4-(Trifluoromethyl)phenyl)-1,2,3,4-tetrahy...)
Affinity DataKi:  4.80nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM390702((S)-N6-(4-(Trifluoromethyl)phenyl)-1,2,3,4-tetrahy...)
Affinity DataKi:  11.3nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent