BDBM391732 US10300058, Compound 2::acrylamide

SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)C(C)=O

InChI Key InChIKey=KBMUKKBYMBZSBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391732   

TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391732(US10300058, Compound 2 | acrylamide )
Affinity DataIC50:  6.20nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391732(US10300058, Compound 2 | acrylamide )
Affinity DataIC50:  552nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent