BDBM391774 2-((7-(4-Cyano-3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-N-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)thiazol-5-carboxamide::US10300067, Example 26

SMILES FC(F)(F)CNC(=O)c1sc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(c2)C(F)(F)F)nc1C(F)(F)F

InChI Key InChIKey=UZCHMABSKIYPKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391774   

TargetAndrogen receptor(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391774(2-((7-(4-Cyano-3-(trifluoromethyl)phenyl)-5,6,7,8-...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent