BDBM391794 2-Chloro-4-(4-((6-fluoro-5-(2-hydroxypropan-2-yl)pyridin-2-yl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7 (8H)-yl)benzonitrile::US10300067, Example 46

SMILES CC(C)(O)c1ccc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(Cl)c2)nc1F

InChI Key InChIKey=DCLOISHMWNCZNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391794   

TargetAndrogen receptor(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391794(2-Chloro-4-(4-((6-fluoro-5-(2-hydroxypropan-2-yl)p...)
Affinity DataIC50:  250nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent