BDBM391833 US10300074, Compd 28::US10300074, Compd 29

SMILES CN[C@@H](C)C(=O)N[C@H]1CCN[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12

InChI Key InChIKey=YYQVMLJSZUXZFS-LREMNVJNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 391833   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM391833(US10300074, Compd 28 | US10300074, Compd 29)
Affinity DataKi:  3.75E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM391833(US10300074, Compd 28 | US10300074, Compd 29)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM391833(US10300074, Compd 28 | US10300074, Compd 29)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM391833(US10300074, Compd 28 | US10300074, Compd 29)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent