BDBM391920 2-((piperidin-4- ylmethyl)amino)-2',3'- dihydrospiro[cyclopropane- 1,1'-indene]-6'-carbonitrile::US10301253, Example 71

SMILES N#Cc1ccc2CCC3(CC3NCC3CCNCC3)c2c1

InChI Key InChIKey=KNOZYLWBBFANSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391920   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM391920(2-((piperidin-4- ylmethyl)amino)-2',3'- dihydrospi...)
Affinity DataIC50:  49.4nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM391920(2-((piperidin-4- ylmethyl)amino)-2',3'- dihydrospi...)
Affinity DataIC50:  44nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent