BDBM392100 US10301272, Example 8/5
SMILES CC(C)(O)CNC(=O)c1nc(CC2CCCCC2)c(s1)-c1ccc(c2ccccc12)S(=O)(=O)NC1(C)COC1
InChI Key InChIKey=ZGXGRJFUQLOGMK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 392100
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 398nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding to RORγ was performed as follows: DNA encodin...More data for this Ligand-Target Pair
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 2nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 3.16nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair