BDBM392308 6-(4-amino-4-methylpiperidin-1-yl)-3-((3-azido-2-chlorophenyl)thio)pyrazin-2-amine::US10301278, Example 11
SMILES CC1(N)CCN(CC1)c1cnc(Sc2cccc(N=[N+]=[N-])c2Cl)c(N)n1
InChI Key InChIKey=GYAKOMITCKMXJI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 392308
Affinity DataIC50: 71nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair