BDBM392327 6-(4-amino-4-phenylpiperidin-1-yl)-3-((2-(trifluoromethyl)pyridin-3-yl)thio)pyrazin-2-amine::US10301278, Example 56
SMILES Nc1nc(cnc1Sc1cccnc1C(F)(F)F)N1CCC(N)(CC1)c1ccccc1
InChI Key InChIKey=MMUCDXXXGYEFAK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 392327
Affinity DataIC50: 542nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair