BDBM392395 N-(2-anilinopyrimidin-5-yl)-3,4- dimethyl-1H-pyrazole-5-carboxamide::US10301280, Compound P-2044

SMILES Cc1n[nH]c(C(=O)Nc2cnc(Nc3ccccc3)nc2)c1C

InChI Key InChIKey=JWFAADHRYYGPOF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392395   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392395(N-(2-anilinopyrimidin-5-yl)-3,4- dimethyl-1H-pyraz...)
Affinity DataKi: <1.00E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392395(N-(2-anilinopyrimidin-5-yl)-3,4- dimethyl-1H-pyraz...)
Affinity DataKi:  1.05E+5nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent