BDBM392572 N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((3-chloro-8-(2- hydroxypropan-2-yl)quinolin-6- yl)methyl)-3-cyano-1H-pyrazole-4- carboxamide::US10301284, Example 58::US10781200, Example 58

SMILES Cc1cc(N)nc(C)c1CNC(=O)c1cn(Cc2cc(c3ncc(Cl)cc3c2)C(C)(C)O)nc1C#N

InChI Key InChIKey=JBHSVGYJIWWDJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392572   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392572(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392572(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent