BDBM392641 N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((3-chloroquinolin-6- yl)methyl)-5-methoxy-1H-pyrrolo[3,2- b]pyridine-3-carboxamide::US10301284, Example 128::US10781200, Example 128

SMILES COc1ccc2n(Cc3ccc4ncc(Cl)cc4c3)cc(C(=O)NCc3c(C)cc(N)nc3C)c2n1

InChI Key InChIKey=VWMBRYCYRNXPCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392641   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392641(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50:  5.50E+3nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392641(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-1-((...)
Affinity DataIC50:  5.50E+3nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent