BDBM392736 Example 36::US10301291, Compound 15f

SMILES Fc1ccc(cc1C(F)(F)F)-c1ncc(CC#N)n1-c1ccnc(NC2CCCN(C2)C(=O)C2CC2)n1

InChI Key InChIKey=AMJPALGZWXBOKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392736   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392736(Example 36 | US10301291, Compound 15f)
Affinity DataIC50:  65nMAssay Description:First of all, after a substrate was inserted into a prepared base reaction buffer solution (20 mM Hepes (pH 75), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent